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KMID : 0363219920300010081
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Korean Journal of Dermatology
1992 Volume.30 No. 1 p.81 ~ p.86
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Treatment of Seborrheic Dermatitis with Itraconazole
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Abstract
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The causative role of Pityrosporum ovalea (P. ovale) in the development of seborrheic dermatitis has been disputed for many decades.
Using Giemsa stain, the number of P. ovale adherant to extruded from one keratinocyte of the scalp were counted in twenty patients with seborrheic dermatitis and twenty control persons.
The result showed that the number of P. ovale in patient with seborrheic dermatitis were significantly higher than in the normal control group. Furthermore not only were the number of P. ovale decreased, but the clinical lesions were also
significantly
improved after a 4 week trial of oral itraconazole in the seborrheic dermatitis group.
From this points of view. P. ovale may be one of the important causative factor of seborrheic dermatitis. (Kor J Dermatol 1992 ; 30 (1) : 81-86)
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